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KMID : 0191120080230040740
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Journal of Korean Medical Science
2008 Volume.23 No. 4 p.740 ~ p.743
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Hypofractionated High-Dose Intensity-Modulated Radiotherapy (60 Gy at 2.5 Gy per Fraction) for Recurrent Renal Cell Carcinoma: A Case Report
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Cho Jae-Ho
Keum Ki-Chang
Lee Yoon-Hee
Lee Chang-Geol
Rha Koon-Ho
Suh Chang-Ok
Kim Gwi-Eon
Seong Jin-Sil
Ahn Joong-Bae
Kim Song-Ie
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Abstract
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A patient with renal cell carcinoma (RCC) developed synchronous bone metastasis with metachronous relapses to the bone and renal fossa. The primary lesion was initially removed surgically, and the metastatic bone lesions and locally recurrent tumours were treated by a high-fractional dose and high-total-dose intensitymodulated radiotherapy (IMRT, 60 Gy at 2.5 Gy per fraction) without significant side effects. All the grossly relapsed tumors underwent complete remission (CR) within a short time after IMRT. To date, CR has been maintained for more than two years. This case study reports the successful treatment of radioresistant RCC using a new scheme that involves a fractionation regimen with a high precision radiotherapy.
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KEYWORD
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Radiotherapy, Intensity-Modulated, Carcinoma, Renal Cell, Radioresistance
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